The skill of business decision-making is extremely important for a successful business. Rationality is a prerequisite for making good decisions, but it is also necessary to understand irrationality and under what circumstances it appears in business decision-making. Also, the role of emotions is an integral part of the decision-making process and it is important to understand them. The first step in decision-making is identifying the problem and gathering relevant information to solve it. By identifying and evaluating alternatives, the best alternative that will fulfill the decision-making requirement is selected. The last step is the implementation and evaluation of the decision itself and its consequences in relation to the business process. In conditions of uncertainty, there is no rule by which the best decision can be made, but with the help of methods and criteria, a decision is made according to which the outcome is the least bad or the best but the most risky. In conditions of risk, the decision-maker is partially or fully aware of the possible outcomes that arise from making a decision, and this provides him with an assessment of the negative consequences of making a decision. The results of the conducted survey on factors in the decision-making process point to the absence of certain stages in the decision-making process, which does not ensure the best decision is made and the solution of the existing problem. The respondents' positive attitude in decision-making is cooperation with others who possess relevant information and knowledge needed to make the best decision and openness to in-depth analysis of the problem, even though it requires a longer period of time to solve it.